Hormone Changes During Perimenopause


A reduction in hormones during perimenopause can absolutely affect motivation, energy, recovery, and even the brain chemistry tied to exercise drive. Many women assume they’ve “lost discipline,” when in reality there are biological shifts happening underneath the surface.

Here’s what’s actually going on:

Estrogen Drops Affect Brain Motivation + Energy

Estrogen helps regulate:

  • Dopamine (motivation/reward)
  • Serotonin (mood)
  • Mitochondrial energy production
  • Blood sugar stability

As estrogen fluctuates and declines, women often experience:

  • Lower motivation
  • Mental fatigue
  • Increased anxiety or depression
  • Reduced “reward feeling” after workouts
  • More exhaustion after exercise

This can make exercise feel harder psychologically and physically.

Testosterone Decline Reduces Drive + Strength

Women produce testosterone too — and it matters for:

  • Muscle maintenance
  • Confidence and competitiveness
  • Exercise stamina
  • Libido and overall drive

Lower testosterone can lead to:

  • Feeling weaker in workouts
  • Less excitement about training
  • Reduced recovery capacity
  • More muscle soreness

Women often describe this as:

“I just don’t feel like myself anymore.”

Progesterone Changes Can Disrupt Sleep

Poor sleep is one of the biggest hidden reasons women stop exercising consistently.

Low progesterone may contribute to:

  • Insomnia
  • Night waking
  • Anxiety
  • Elevated cortisol

When sleep quality drops:

  • Recovery drops
  • Motivation drops
  • Cravings increase
  • Exercise feels punishing instead of energizing

Cortisol Becomes More Dominant

During perimenopause, stress hormones can become dysregulated.

High cortisol can cause:

  • Fatigue
  • Belly fat gain
  • Muscle breakdown
  • Blood sugar swings
  • Overwhelm and burnout

Women who previously thrived on intense cardio may suddenly feel:

  • Inflamed
  • Exhausted
  • Unmotivated

Their body is often asking for a different training strategy.

Muscle Loss Makes Exercise Feel Harder

Declining estrogen accelerates muscle loss and reduces insulin sensitivity.

This means:

  • Workouts feel harder than they used to
  • Recovery takes longer
  • Joints ache more
  • Energy crashes happen faster

If every workout suddenly feels harder with fewer results, motivation naturally declines.

The Important Part:

This is not laziness

For many women, the body they used to rely on changes rapidly during perimenopause. The solution is usually not “more willpower.” It’s:

  • Better recovery
  • More protein
  • Strength training
  • Sleep optimization
  • Hormone evaluation
  • Smarter exercise programming
  • Nervous system regulation

What Helps Most

  1. Prioritize strength training over excessive cardio
  2. Increase protein intake
  3. Walk daily to stabilize cortisol
  4. Improve sleep aggressively
  5. Check iron, vitamin D, thyroid, testosterone, and estrogen levels
  6. Reduce all-or-nothing exercise thinking
  7. Focus on consistency, not intensity

A lot of women regain their energy once they stop training like they’re still 25 and start supporting the hormonal reality of midlife instead of fighting it.

Alix Shutello

It took me 12 years to make my menopause transition (age 44-56). In that time I learned a lot about what it takes to make necessary changes to keep healthy and comfortable during this major biological change. I captured the steps I took in my book, Make It a Fair Fight, The Three-Step Battle Plan to Win the War against Menopause symptoms. You can read more in the Book Description tab. I've been an advocate for women's health, and, as a biologist myself, I began to study the science of hormone decline in women.

Read more from Alix Shutello

Let's Make It a Fair Fight Every year, millions of women step into perimenopause—often without guidance, without support, and without the dignity we deserve. For generations, the medical system failed us in ways that were not just inadequate, but deeply dehumanizing. Women were brushed aside, branded hysterical and told our pain was imaginary. Our symptoms were minimized, our voices dismissed and treatments were administered for convenience, not compassion. Even now, the legacy of that...